Rabaptin-5α rabbit pAb - ES7966

Rabaptin-5α rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7966-50, ES7966-100

Citations, Manuals and MSDS Available upon request.

Background: function:Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A., PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity., similarity:Belongs to the rabaptin family., subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2.,

Alternate Name: RABEP1; RAB5EP; RABPT5; RABPT5A; Rab GTPase-binding effector protein 1; Rabaptin-4; Rabaptin-5; Rabaptin-5alpha; Renal carcinoma antigen NY-REN-17

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human RABEP1. AA range:549-598

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 9135

Human SWISS Prot NO: Q15276

Subcellular Location: Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle.

Research Use Only