Rad23B Polyclonal Antibody - BT-AP07605

Rad23B Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07605-20, BT-AP07605-50, BT-AP07605-100

Citations, Manuals and MSDS Available upon request.

Background: RAD23 homolog B, nucleotide excision repair protein encoded by RAD23B is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). RAD23 homolog B, nucleotide excision repair protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. RAD23 homolog B, nucleotide excision repair protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. RAD23 homolog B, nucleotide excision repair protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus RAD23 homolog B, nucleotide excision repair protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: RAD23B

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Rad23B Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 43171

UniProt Accession: Human: P54727; Mouse: P54728; Rat: Q4KMA2

Synonyms: RAD23B; UV excision repair protein RAD23 homolog B; HR23B; hHR23B; XP-C repair-complementing complex 58 kDa protein; p58

GeneID: Human: 5887; Mouse: 19359; Rat: 298012

Research Use Only