Rad50 (phospho-Ser635) Rabbit Polyclonal Antibody - RA29198

Rad50 (phospho-Ser635) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29198-50, RA29198-100

Citations, Manuals and MSDS Available upon request.

Background: RAD50 double strand break repair protein (RAD50) Homo sapiens The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)

Applications: WB

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 10111

Protein MW (KDa): 153

SWISS: Q92878

Source: Rabbit

Research Use Only