Rad50 Polyclonal Antibody
Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sizes: 50µl, 100µl
Catalogue Numbers: BZ16840-50, BZ16840-100
Swiss-Prot: Q92878
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, ICC/IF
All Applications: WB: 1/500-1/1000 IF: 1/50-1/200
Background: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Calculated MW: 154 kDa; Observed MW: 154 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Rad50 in Jurkat lysates; using Rad50 antibody.
Alternative Name: RAD50; DNA repair protein RAD50; hRAD50
Immunogen: A synthesized peptide derived from human Rad50
Conjugate: Unconjugated
Modification: Unmodified