RAD51B Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A6962-20, A6962-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.
Synonyms: REC2; R51H2; RAD51L1; RAD51B
GeneID: 5890
Swiss-Prot: O15315
Reactivity: Mouse, Rat
Calculated Molecular Weight: 42kDa
Observed Molecular Weight: 42kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human RAD51B (NP_598193.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse kidney, Rat kidney
Cellular Location: Nucleus
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.