Rad51C Polyclonal Antibody - BT-AP07610

Rad51C Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07610-20, BT-AP07610-50, BT-AP07610-100

Citations, Manuals and MSDS Available upon request.

Background: RAD51C is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. RAD51 paralog C can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in RAD51C are associated with Fanconi anemia-like syndrome. RAD51C is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: RAD51C

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Monkey

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Rad51C Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 42190

UniProt Accession: Human: O43502; Mouse: Q924H5

Synonyms: RAD51C; RAD51L2; DNA repair protein RAD51 homolog 3; R51H3; RAD51 homolog C; RAD51-like protein 2

GeneID: Human: 5889

Research Use Only