Product Description

Rad51C Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21224-50, RA21224-100

Citations, Manuals and MSDS Available upon request.

Background: RAD51 paralog C (RAD51C) Homo sapiens This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: RAD51C; RAD51L2; DNA repair protein RAD51 homolog 3; R51H3; RAD51 homolog C; RAD51-like protein 2

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Monkey

GeneID (Human): 5889

Protein MW (KDa): 50

SWISS: O43502

Source: Rabbit

Research Use Only