Raftlin rabbit pAb - ES5314

Raftlin rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5314-50, ES5314-100

Citations, Manuals and MSDS Available upon request.

Background: function:May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling., similarity:Belongs to the raftlin family., subcellular location:Associates with lipid rafts., tissue specificity:Specifically expressed by B-cells (at protein level).,

Alternate Name: RFTN1; KIAA0084; MIG2; Raftlin; Cell migration-inducing gene 2 protein; Raft-linking protein

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human RFTN1. AA range:432-481

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 65kD

Human Gene ID: 23180

Human SWISS Prot NO: Q14699

Subcellular Location: Cell membrane; Lipid-anchor. Cytoplasm. Membrane raft. Endosome. Early endosome. Translocates from cytoplasm to cell membrane where it colocalizes with poly (I:C) and then moves to endosomes where it colocalizes with TLR3 (PubMed:21266579). Translocates from cytoplasm to cell membrane where it colocalizes with TLR4 and then together with TLR4 moves to endosomes, upon lipopolysaccharide stimulation (PubMed:27022195).

Research Use Only