RALBP1 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS91151-50, BS91151-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q15311(Human) Q62172(Mouse) Q62796(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC FC
All Applications: WB:1:1,000-1:5,000
FC:1:50-1:100
IHC:1:50-1:200
Background: Ral A and Ral B constitute a distinct subfamily of Ras-related GTPases (i.e., GDP/GTP binding proteins). Ral proteins are activated by a unique nucleotide exchange factor, Ral GDS, and deactivated by a distinct GTPase-activating protein. Unlike Ras proteins, Ral A and Ral B fail to induce transformed foci when activated variants are expressed in various recipient cells. A potential downstream target of Ral, designated Ral BP-1, has been shown to contain a Rho-GTPase-activating domain. This Rho-GTPase-activating domain interacts preferentially with the Rho family member Cdc42. A Ras/Ral signaling pathway has been reported to mediate phospholipase D (PLD) activation by v-Src, thus indicating PLD as another downstream target of Ral A.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: RALBP1 polyclonal antibody detects endogenous levels of RALBP1 protein.
Bioworld Molecular Weight: 95 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of RALBP1 on different lysates using anti-RALBP1 antibody at 1/1,000 dilution.
Positive control:
Lane 1: HCT116
Lane 2: Jurkat
Lane 3: 293T, Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-RALBP1 antibody. Counter stained with hematoxylin.
Alternative Name: DNP-SG ATPase, RALBP1, RLIP1, 76 kDa Ral-interacting protein, 76-kDa Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, Ral-interacting protein 1, 76-KD, RalA-binding protein 1, RalBP1, RBP1, RIP1, RLIP1, RLIP76,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified