RanBP9 Monoclonal Antibody-MB0163

RanBP9 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB0163-50, MB0163-100

Product: Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q96S59

Host: Mouse

Reactivity: Human

Applications: WB, IP, ICC

All Applications: WB: 1:1000 ICC: 1:100~300 IP: 1:50~100

Background: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B.

Purification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of RanBP9 and does not cross-react with related proteins

Bioworld Molecular Weight: Predicted band size: 78KDa
Observed band size: 95KDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot detection of RANBP9 in Jurkat, MOLT-4 and CEM cell lysates and using RANBP9 antibody (1:1000 diluted)., Immunocytochemistry stain of Hela using RANBP9 antibody (1:300)., Immunoprecipitation analysis of Hela cell lysates using RANBP9 antibody

Alternative Name: BPM-L; BPM90; Ran-binding protein M; RanBPM; RanBP7; BPM-L; BPM90; RANBPM; RanBP7

Immunogen: Recombinant full length Human RanBP9.

Conjugate: Unconjugated

Modification: Unmodified