Product Description

RANBP9 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB67182-50, MB67182-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: RanBP9 (RanBPM) is a Ran binding protein ubiquitously expressed and highly conserved in different organisms. It is a scaffolding protein that was identified as an interacting protein of MET inducing Ras- Erk activation. Several domains and motifs regμlate the nuclear and cytoplasmic localization of RanBP9. Research studies indicate that RanBP9 might contribute to the pathogenesis of Alzheimer’s Disease (AD). In addition to elevated expression levels in AD samples, this may involve interaction of RanBP9 with APP and BACE1 promoting endocytosis of APP and increased BACE1 mediated cleavage of APP to generate β-amyloid peptides.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB, IHC

Alternate Names: RANBPM, Ran-binding protein 9, RanBP9, BPM-L, BPM90, Ran-binding protein M, RanBPM, RanBP7

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human RANBP9. The exact sequence is proprietary.

Dilution: WB (1/1000 - 1/2000), IHC (1/50 - 1/200)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of RANBP9 protein.

Molecular Weight: ~ 96 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96S59

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only