Rap1A Polyclonal Antibody-BS78338

Rap1A Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS78338-50, BS78338-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P62834

Host: Rabbit

Reactivity: Mouse, Rat

Applications: IHC

All Applications: IHC,1:50 - 1:200

Background: This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Unmodification

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: RAP1A; C21KG; G-22K; KREV-1; KREV1; RAP1; SMGP21

Immunogen: Recombinant fusion protein of human Rap1A(NP_002875.1).

Conjugate: Unconjugated

Modification: Unmodified