Raptor (Phospho-Ser792) Rabbit Polyclonal Antibody - BT-AP12231

Raptor (Phospho-Ser792) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12231-20, BT-AP12231-50, BT-AP12231-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase| and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase| and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cell biology; Epigenetics and nuclear signaling; Signal transduction

Target Protein: RPTOR

Applications: WB

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Raptor

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8N122; Mouse: Q8K4Q0

Synonyms: Raptor;Ser792; Regulatory-associated protein of mTOR; Raptor; p150 target of rapamycin; TOR-scaffold protein

GeneID: Human: 57521

Research Use Only