Product Description

Raptor Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40185-50, BS40185-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The regμlatory associated protein of mTOR (Raptor) was identified as an mTOR binding partner that mediates mTOR signaling to downstream targets. Raptor binds to mTOR substrates, including 4E-BP1 and p70 S6 kinase, through their TOR signaling (TOS) motifs and is required for mTOR-mediated phosphorylation of these substrates. Binding of the FKBP12-rapamycin complex to mTOR inhibits the mTOR-raptor interaction, suggesting a mechanism for rapamycin's specific inhibition of mTOR signaling. This mTOR-raptor interaction and its regμlation by nutrients and/or rapamycin is dependent on a protein called GβL.

Category: Primary Antibody

Reactivity: Human Mouse Rat

Host: Rabbit

Applications: WB, IHC, ICC/IF, IP, FC

Alternate Names: RPTOR, KOG1, KIAA1303, RAPTOR, Mip1,

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthesized peptide derived from human Raptor

Dilution: WB 1:500~1:1000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:30 FC 1:30

Purification: Affinity-chromatography

Specificity: Raptor Antibody detects endogenous levels of Raptor

Molecular Weight: 149kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8N122

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only