RASGRP3 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS70921-50, BS70921-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q8IV61
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB IF
All Applications: WB: 1:500~1:2000
IF: 1:50~1:200
Background: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: RASGRP3 polyclonal antibody detects endogenous levels of RASGRP3 protein.
Bioworld Molecular Weight: ~ 78 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western Blot analysis of extracts of various cells, using RASGRP3 antibody.
Alternative Name: GRP3;
Immunogen: Recombinant protein of human RASGRP3.
Conjugate: Unconjugated
Modification: Unmodified