RASSF1 Monoclonal Antibody - RA11933

RASSF1 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11933-50, RA11933-100

Citations, Manuals and MSDS Available upon request.

Background: Ras association domain family member 1 (RASSF1) Homo sapiens This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011],

Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB

Species Cross-Reactivity: Human

GeneID (Human): 11186

SWISS: Q9NS23

Source: Mouse

Research Use Only