Product Description

RASSF5 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8875-50, BS8875-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimμlation to integrin activation. Isoform 2 stimμlates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resμlting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regμlation of microtubμle growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regμlation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Ras association domain-containing protein 5, New ras effector 1, Regμlator for cell adhesion and polarization enriched in lymphoid tissues, RAPL, RASSF5, NORE1, RAPL

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human RASSF5.

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: RASSF5 polyclonal antibody detects endogenous levels of RASSF5 protein.

Molecular Weight: ~ 37, 45kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8WWW0

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only