Product Description

Rb Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11934-50, RA11934-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: RB transcriptional corepressor 1 (RB1) Homo sapiens The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],

Reactivity: Human

Host: Mouse

Applications: IHC-p, IF(paraffin section), ELISA

Alternate Names: RB1, Retinoblastoma-associated protein, p105-Rb, pRb, Rb, pp110

Clonality: Monoclonal

Dilution: Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Storage: -20°C/1 year

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Human Gene ID: 5925

Research Use Only