Product Description

Rb Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11934-50, RA11934-100

Citations, Manuals and MSDS Available upon request.

Background: RB transcriptional corepressor 1 (RB1) Homo sapiens The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 5925

SWISS: P06400

Source: Mouse

Research Use Only