Rb (phospho-Ser807/811) Rabbit Polyclonal Antibody - RA29284

Rb (phospho-Ser807/811) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29284-50, RA29284-100

Citations, Manuals and MSDS Available upon request.

Background: RB transcriptional corepressor 1 (RB1) Homo sapiens The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: Retinoblastoma-associated protein (p105-Rb) (pRb) (Rb) (pp110)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5925

Protein MW (KDa): 106

SWISS: P06400

Source: Rabbit

Research Use Only