Rb Polyclonal Antibody - RA29293

Rb Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29293-50, RA29293-100

Citations, Manuals and MSDS Available upon request.

Background: RB transcriptional corepressor 1 (RB1) Homo sapiens The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5925

Protein MW (KDa): 105

SWISS: P06400

Source: Rabbit

Research Use Only