RBP4 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS91161-50, BS91161-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P02753(Human)
Host: Rabbit
Reactivity: Human
Applications: WB, IHC
All Applications: WB:1:500-1:2,000
IHC:1:50-1:200
Background: Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with insulin resistance have generated research into the possible roles the protein
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: RBP4 polyclonal antibody detects endogenous levels of RBP4 protein.
Bioworld Molecular Weight: 23 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of RBP4 on human serum using anti- RBP4 antibody at 1/1,000 dilution., Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-RBP4 antibody. Counter stained with hematoxylin.
Alternative Name: PRBP, RBP, RBP4, OTTHUMP00000020114, OTTHUMP00000020115, OTTHUMP00000020116, Plasma retinol binding protein 4, Plasma retinol-binding protein, Plasma retinol-binding protein(1-176), PRBP, PRO2222, RBP, RBP4, RDCCAS, RET4, Retinol binding protein 4, Retinol binding protein 4 interstitial, Retinol binding protein 4 plasma,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified