RCC1 rabbit pAb - ES8532

RCC1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8532-50, ES8532-100

Citations, Manuals and MSDS Available upon request.

Background: disease:Patients with Raynaud disease produce antibodies that bind to RCC1., function:Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1/Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA., similarity:Contains 7 RCC1 repeats., subcellular location:Becomes dispersed throughout the cytoplasm during mitosis.,

Alternate Name: RCC1 CHC1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: WB 1:500-2000, IHC-p 1:50-200 ELISA 1:10000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthetic peptide from human protein at AA range: 301-350

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 45kD

Human Gene ID: 1104

Human SWISS Prot NO: P18754

Subcellular Location: Nucleus. Chromosome. Cytoplasm. Predominantly nuclear in interphase cells (PubMed:12194828). Binds to mitotic chromosomes (PubMed:12194828, PubMed:17435751, PubMed:20668449).

Research Use Only