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Recombinant Acetyl-Histone H3 Monoclonal Antibody - E-AB-81524

Recombinant Acetyl-Histone H3 Monoclonal Antibody - E-AB-81524

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Recombinant Acetyl-Histone H3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: E-AB-81524-50, E-AB-81524-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: Acetyl-Histone H3

Target Synonym: H3 histone family; member A; H3/A; H31; H3FA; Hist1h3a; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; histone 1; H3a; Histone cluster 1; H3a; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC-P, IF

Isotype: IgG

Clonality: Rabbit Monoclonal

Clone No.: R08-4A0

UNIProt ID: P68431

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Concentration: 300 μg/mL

Immunogen: A synthetic acetyl-peptide corresponding to residues surrounding Lys27 of human Histone H3

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification Method: Affinity Purified

Dilution: WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100

Calculated MW: 15kDa

Observed MW: 17kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only