Product Description

Recombinant Cavia porcellus IL-1b/IL-1 beta/IL-1F2 Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSQ050092-10, PKSQ050092-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: IL-1 beta; IL-1F2

Target Synonym: Interleukin-1 beta; IL-1 beta; IL1B; IL1b

UNIProt ID: Q9WVG1

Target Species: Cavia porcellus

Expression Host: E.coli

Fusion Tag: C-His

Accession: Q9WVG1

Background: Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Sequence: Thr115-Ser266

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 18.2 kDa

Observed MW: 16-19 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only