Recombinant Cynomolgus macaques ABL1 protein (His tag)
Size: 100μg
Catalogue Numbers: PDEC100003-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: ABL1
Target Synonym: Abelson tyrosine protein kinase 1; ABL 1; bcr/abl; JTK7; p150; Proto-oncogene c-Abl; v abl
UNIProt ID: A0A2K5X6F2
Research Areas: Signal Transduction; Cancer; Epigenetics and Nuclear Signaling; Neuroscience
Target Species: Cynomolgus macaques
Expression Host: E.coli
Fusion Tag: N-His
Accession: A0A2K5X6F2
Background: Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
Sequence: Met 1-Phe 264
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 28.93 kDa
Observed MW: 35 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only