Recombinant Human AIMP2 protein (his tag)
Size: 100μg
Catalogue Numbers: PDEH100437-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: AIMP2
Target Synonym: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; AIMP2; Multisynthase complex auxiliary component p38; Protein JTV-1
UNIProt ID: Q13155
Research Areas: Cell Biology; Neuroscience
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
Accession: Q13155
Background: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Sequence: Met 1-Lys 320
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 35.09 kDa
Observed MW: 30 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only