Recombinant Human AKR1C2 Protein
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032054-10, PKSH032054-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: AKR1C2
Target Synonym: Aldo-Keto Reductase Family 1 Member C2; 3-Alpha-HSD3; Chlordecone Reductase Homolog HAKRD; Dihydrodiol Dehydrogenase 2; DD-2; DD2; Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein; DD/BABP; Trans-1; 2-Dihydrobenzene-1; 2-Diol Dehydrogenase; Type III 3-Alpha-Hydroxysteroid Dehydrogenase; AKR1C2; DDH2
UNIProt ID: P52895
Research Areas: Signal Transduction; Cancer; metabolism;
Target Species: Human
Expression Host: E.coli
Fusion Tag: None
Accession: P52895
Background: Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).
Sequence: Met 1-Tyr323
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 36.7 kDa
Observed MW: 35 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only