Recombinant Human ApoA1 protein (His tag)
Sizes: 20μg, 100μg
Catalogue Numbers: PDMH100047-20, PDMH100047-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: ApoA1
Target Synonym: Apolipoprotein A-I; Apo-AI; ApoA-I; Apolipoprotein A1; APOA1
UNIProt ID: P02647
Research Areas: Signal Transduction; Cardiovascular; Neuroscience; Cancer; metabolism;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-His
Accession: P02647
Background: Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and circulatory system. APOA1 is the main component of high density lipoprotein (HDL) in plasma and is involved in the esterification of cholesterol as a cofactor of lecithin-cholesterol acyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters; and thus play a major role in cholesterol efflux from peripheral cells. As a major component of the HDL complex; APOA1 helps to clear cholesterol from arteries. APOA1 is also characterized as a prostacyclin stabilizing factor; and thus may have an anticlotting effect. Defects in encoding gene may result in HDL deficiencies; including Tangier disease; and with systemic non-neuropathic amyloidosis. Men carrying a mutation may develop premature coronary artery disease.
Sequence: Met1-Gln267
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 29.26 kDa
Observed MW: 30 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only