Recombinant Human ASB13 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032070-10, PKSH032070-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: ASB13
Target Synonym: Ankyrin repeat and SOCS box protein 13; ASB13;
UNIProt ID: Q8WXK3
Research Areas: Cell biology
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-6His
Accession: Q8WXK3
Background: Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Sequence: Met 1-Asn278
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4, 4M Urea.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 31.4 kDa
Observed MW: 28 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only