Product Description

Recombinant Human BMF/Bcl2 modifying factor Protein (His Tag)

Size: 100μg

Catalogue Number: PKSH030590-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: BMF, Bcl2 modifying factor

Target Synonym: BMF

UNIProt ID: Q96LC9

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

Accession: Q96LC9-1

Background: BMF(Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. BMF is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Sequence: Met 1-Arg184

Purity: > 85 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile 50mM Tris, 0.1% Brij35, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: Please contact us for more information.

Calculated MW: 22.3 kDa

Observed MW: 25 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only