Recombinant Human CD52 Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP01429-10, RP01429-20, RP01429-50, RP01429-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human CD52 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly25-Ser36) of human CD52 (Accession #NP_001794.2) fused with a Fc, Avi tag at the C-terminus.
Alternate Names: CD52, CDW52, EDDM5
SWISS: P31358
GeneID: 1043
Species: Human
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.
Bio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD52 Protein at 5 μg/mL (100 μL/well) can bind SIGLEC10 with a linear range of 20.49-455.65ng/mL.
Source: HEK293 cells
Tag: C-hFc&Avi
Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Antigen Sequence: GQNDTSQTSSPS
Endotoxin: < 0.1 EU/μg of the protein by LAL method.
Research Use Only