Recombinant Human CGA&CGB3 Heterodimer Protein (His & Flag Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033665-10, PKSH033665-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: CGA&CGB3 Heterodimer
Target Symptom: Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB
Research Area: Signal Transduction; Neuroscience; Cancer; Developmental Biology; metabolism;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-Flag & C-His
UNIProt ID: P01215&P0DN86
Accession: P01215&P0DN86
Background: Glycoprotein hormones alpha chain, also known as CGA, belongs to the glycoprotein hormones subunit alpha family. The subunit of CGA is a heterodimer consists of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. It has positive regulation of cell migration, cell proliferation and transcription from RNA polymerase II promoter and participates in the peptide hormone processing and signal transduction.
Sequence: Ala25-Ser116&Ser21-Gln165
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 11.6&16.6 kDa
Observed MW: 22&30-35 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only