Recombinant Human Colipase/CLPS Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP00125-10, RP00125-20, RP00125-50, RP00125-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human Colipase/CLPS Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Met1-Gln112) of human CLPS/Colipase (Accession #NP_001823.1) fused with a 6×His tag at the C-terminus.
Alternate Names: CLPS, colipase
SWISS: P04118
GeneID: 1208
Species: Human
Purity: ≥ 90 % as determined by SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: The protein is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
Source: HEK293 cells
Tag: C-His
Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Antigen Sequence: MEKILILLLVALSVAYAAPGPRGIIINLENGELCMNSAQCKSNCCQHSSALGLARCTSMASENSECSVKTLYGIYYKCPCERGLTCEGDKTIVGSITNTNFGICHDAGRSKQ
Endotoxin: < 0.1 EU/μg of the protein by LAL method.
Research Use Only