Recombinant Human CTGF/CCN2 Protein (Fc Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032276-10, PKSH032276-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: CTGF; CCN2
Target Synonym: Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; CTGF; IGFBP8
UNIProt ID: P29279
Research Areas: Cardiovascular; immunology
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-Fc
Accession: P29279
Background: CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family; which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT); a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).
Sequence: Gln27-Ala349
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 62.6 kDa
Observed MW: 88 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only