Recombinant Human CTNNB1 Protein
Size: 100μg
Catalogue Numbers: PDEH100082-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: CTNNB1
Target Synonym: Catenin beta-1; Beta-catenin; CTNNB; OK; SW-cl.35; PRO2286
UNIProt ID: P35222
Research Areas: Cancer; Cardiovascular; Neuroscience; Signal Transduction
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
Accession: P35222
Background: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome.
Sequence: Met131-Tyr670
Purity: > 85 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 59 kDa
Observed MW: 59 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only