Recombinant Human Cystatin C/CST3 Protein (Human Cells)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032321-10, PKSH032321-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Cystatin C; CST3
Target Synonym: Cystatin-C; Cystatin-3; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin; CST3
UNIProt ID: P01034
Research Areas: Tags & Cell Markers; Cell biology; Cardiovascular; Stem cells
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: None
Accession: P01034
Background: Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B; H; K; L and S. As an inhibitor of cysteine proteinases; Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently; it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition); such as Alzheimer's disease.
Sequence: Ser27-Ala146
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 10mM PB, 200mM Nacl, pH6.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 13.3 kDa
Observed MW: 15 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only