Recombinant Human GFAP protein
Sizes: 10ug, 50ug
Catalogue Number: RP03141-10, RP03141-50
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human GFAP Protein is produced by E. coli expression system. The target protein is expressed with sequence (Leu292-Met432) of Human GFAP (Accession #NP_002046.1) fused with His tag at the N-terminus.
Alternate Names: Glial fibrillary acidic protein, GFAP
SWISS: P14136
GeneID: 2670
Species: Human
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells but its exact function remains poorly understood.
Source: E. coli
Tag: N-His
Formulation: Lyophilized from a 0.22 μm filtered solution of 20mM Tris-HCl, 10% Trehalose, 0.05% Tween 80, pH 8.5. Contact us for customized product form or formulation.
Antigen Sequence: LTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
Endotoxin: < 1 EU/μg of the protein by LAL method.
Research Use Only