Recombinant Human GGACT Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033272-10, PKSH033272-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: GGACT
Target Symptom: Gamma-Glutamylaminecyclotransferase; GGACT; AIG2-Like Domain-Containing Protein 1; A2LD1
Research Area: Signal Transduction; metabolism;
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-6His
UNIProt ID: Q9BVM4
Accession: Q9BVM4
Background: Gamma-Glutamylaminecyclotransferase is an enzyme that converts gamma-glutamylamines to free amines and 5-oxoproline which belongs to the gamma-glutamylcyclotransferase family. It shows high activity toward gamma-glutamyl-epsilon-lysine, derived from the breakdown of fibrin and contributes to degradation of proteins cross-linked by transglutaminases. It degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. This protein adopts the newly identified cyclotransferase fold, observed in Gamma-Glutamylcyclotransferase, an enzyme with activity toward gamma-glutamyl-alpha-amino acids.
Sequence: Met 1-Arg153
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 19.5 kDa
Observed MW: 18 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only