Recombinant Human Grancalcin/GCA Protein
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032506-10, PKSH032506-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Grancalcin; GCA
Target Synonym: Grancalcin; GCA; GCL
UNIProt ID: P28676
Research Areas: immunology
Target Species: Human
Expression Host: E.coli
Fusion Tag: None
Accession: P28676
Background: Grancalcin (GCA) is a cytoplasmic granule membrane protein that contains 4 EF-hand domains. GCA is calcium-binding protein and particularly abundant in human neutrophils. GCA is highly expressed in bone marrow; and it can be detected in neutrophils and macrophages. Calcium-binding protein GCA cooperates with SRI and LCP1; so it may play a role in the adhesion of neutrophils to fibronectin. GCA also may play a role in the formation of focal adhesions.
Sequence: Met 1-Ile217
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM EDTA, pH 8.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 24.0 kDa
Observed MW: 26 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only