Recombinant Human IL-4 Protein
Size: 100μg
Catalogue Numbers: PDEH100061-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: IL-4
Target Synonym: Interleukin-4; IL4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra
UNIProt ID: P05112
Research Areas: Cancer; Cardiovascular; Immunology;
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
Accession: P05112
Background: Participates in at least several B-cell activation processes as well as of other cell types.
It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.
Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
Sequence: His25-Ser153
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 15 kDa
Observed MW: 16 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only