Recombinant Human Integrin Beta-1/ITGB1 (C-6His)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033841-10, PKSH033841-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Integrin Beta-1; ITGB1
Target Symptom: Integrin Beta-1; Fibronectin Receptor Subunit Beta; VLA-4 Subunit Beta; CD29; ITGB1; FNRB; MDF2; MSK12
Research Area: Signal Transduction; Microbiology; Neuroscience; Cancer; Developmental Biology; metabolism; Stem cells
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
UNIProt ID: P05556
Accession: P05556
Background: Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and reelin.
Sequence: Gln21-Asp728
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 79.4 kDa
Observed MW: 100-130 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only