Recombinant Human KIR2DL4/CD158D Protein (His Tag)
Size: 50μg
Catalogue Numbers: PKSH032675-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: KIR2DL4; CD158D
Target Synonym: Killer Cell Immunoglobulin-Like Receptor 2DL4; CD158 Antigen-Like Family Member D; G9P; Killer Cell Inhibitory Receptor 103AS; KIR-103AS; MHC Class I NK Cell Receptor KIR103AS; CD158d; KIR2DL4; CD158D; KIR103AS
UNIProt ID: Q99706
Research Areas: immunology
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: Q99706
Background: Killer cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.
Sequence: Trp22-His242
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 25.3 kDa
Observed MW: 37 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only