Recombinant Human LTA4H Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032704-10, PKSH032704-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: LTA4H
Target Synonym: Leukotriene A-4 hydrolase; LTA-4 hydrolase; Leukotriene A(4) hydrolase; LTA4; LTA4H
UNIProt ID: P09960
Research Areas: Cancer; immunology; metabolism
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: P09960
Background: LTA4H, which is short for Leukotriene A-4 hydrolase, is a 611 aa. protein. It belongs to the peptidase M1 family, and exists in cytoplasm. This protein has at least 4 isforms produced by alternative splicing, and two of them are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts. LTA4H involves in lipid metabolism and leukotriene B4 biosynthesis. It is a epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. It also has aminopeptidase activity
Sequence: Met 1-Asp611
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM MES, 2mM EDTA, 20%Glycerol, pH5.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 70.3 kDa
Observed MW: 60-70 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only