Recombinant Human LTBR/TNFRSF3 Protein (Fc Tag)
Size: 50μg
Catalogue Numbers: PKSH032718-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: LTBR; TNFRSF3
Target Synonym: Tumor Necrosis Factor Receptor Superfamily Member 3; Lymphotoxin-Beta Receptor; Tumor Necrosis Factor C Receptor; Tumor Necrosis Factor Receptor 2-Related Protein; Tumor Necrosis Factor Receptor Type III; TNF-RIII; TNFR-III; LTBR; D12S370; TNFCR; TNFR3; TNFRSF3
UNIProt ID: P36941
Research Areas: Signal Transduction; Cell biology; epigenetics and nuclear signal;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-Fc
Accession: P36941
Background: Tumor necrosis factor receptor superfamily member 3; also known as Lymphotoxin-beta receptor; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor type III; LTBR; TNFCR; TNFR3 and TNFRSF3; is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types; but not on T and B lymphocytes. LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of LTBR can trigger apoptosis. In addition; LTBR can lead to the release of the cytokine interleukin 8.
Sequence: Gln31-Met227
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 48.8 kDa
Observed MW: 61 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only