Recombinant Human/Mouse/Rat mature BMP-2 Protein
Sizes: 10ug, 20g, 50ug, 100ug
Catalogue Numbers: RP02510S-10, RP02510S-20, RP02510S-50, RP02510S-100
Citations, Manuals and MSDS Available upon request.
Description: Recombinant Human/Mouse/Rat mature BMP-2 Protein is produced by Escherichia coli expression system. The target protein is expressed with sequence (Ala284-Arg396) of Human/Mouse/Rat BMP-2 (NP_001191.1) fused with no tag.
Alternate Names: BDA2, BMP2A, BMP2
SWISS: P12643
GeneID: 650
Species: Human,Mouse,Rat
Purity: ≥ 95 % as determined by SDS-PAGE.
Storage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Background: BMP-2 like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor interaction. It is also involved in cardiac cell differentiation and epithelial to mesenchymal transition. Like many other proteins from the BMP family, BMP-2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2 may be involved in white adipogenesis and may have metabolic effects.
Bio-Activity: Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.The ED50 for this effect is 24.59-98.36 ng/mL, corresponding to a specific activity of 1.02×10^4 ~4.07×10^4 units/mg.
Source: E.coli
Tag: No tag
Formulation: Lyophilized from a 0.22 μm filtered solution of 0.1% TFA, 30% ACN. Contact us for customized product form or formulation.
Antigen Sequence: AKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
Endotoxin: < 1 EU/μg of the protein by LAL method.
Research Use Only