Recombinant Human/Mouse/Rat/Rhesus/Canine BMP-2 Protein (Fc Tag)(Active)
Size: 100μg
Catalogue Number: PKSH031985-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: BMP-2
Target Symptom: BDA2; BDA2A; BMP-2; BMP2A; BMP2
Research Area: Signal Transduction; Cardiovascular; Cancer; Stem cells
Target Species: Human
Expression Host: HEK293 Cells
Application: ELISA
Fusion Tag: C-hFc
Accession: NP_001191.1
Background: BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
Activity: Measured by its ability to bind recombinant human Nog-Fc, human ALK3-Fch, mouse ALK3-Fch, human BMPR-II-Fc in functional ELISA.
Sequence: Gln 283-Arg 396
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 39.5 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only