Recombinant Human Natriuretic Peptides B/NPPB Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033585-10, PKSH033585-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: NPPB
Target Symptom: Natriuretic Peptides B; Gamma-Brain Natriuretic Peptide; NPPB
Research Area: Signal Transduction; Cardiovascular; Neuroscience;
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: P16860
Accession: P16860
Background: Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions; such as diuresis; natriuresis; vasorelaxation; which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water; improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.
Sequence: His27-His134
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, 1mM DTT, 20% Glycerol, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 14.2 kDa
Observed MW: 16 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only