Recombinant Human NLGN4X Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032797-10, PKSH032797-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: NLGN4X
Target Synonym: Neuroligin-4 X-Linked; Neuroligin X; HNLX; NLGN4X; KIAA1260; NLGN4
UNIProt ID: Q8N0W4
Research Areas: Neuroscience
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: Q8N0W4
Background: Neuroligin 4, X-Linked (NLGN4X) is a single-pass type I membrane protein that belongs to the type-B carboxylesterase/lipase family. NLGN4X is detected at higher levels in heart and at lower levels in the liver, skeletal muscle, and pancreas. NLGN4X is a putative neuronal cell surface protein involved in cell-cell-interactions. NLGN4X may act as splice site-specific ligands for β-neurexins. It has been shown that NLGN4X is involved in the formation and remodeling of central nervous system synapses. NLGN4X also interacts with discs, large (Drosophila) homolog 4 (DLG4). Defects in NLGN4X have been associated with autism and Asperger syndrome.
Sequence: Gln42-Ser676
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 72.5 kDa
Observed MW: 95 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only