Recombinant Human NOTCH3 protein (His tag)
Size: 100μg
Catalogue Numbers: PDEH100369-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: NOTCH3
Target Synonym: Neurogenic locus notch homolog protein 3; NOTCH3
UNIProt ID: Q9UM47
Research Areas: Cardiovascular; Epigenetics and Nuclear signaling; Neuroscience; Stem Cells
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
Accession: Q9UM47
Background: Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring cell. In both vertebrates and invertebrates, Notch signaling is important for specifying cell fates and for defining boundaries between different cell types.
Sequence: Val 1289-Cys 1458
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 18.59 kDa
Observed MW: 20 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only