Recombinant Human PADI4 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032973-10, PKSH032973-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: PADI4
Target Synonym: Protein-Arginine Deiminase Type-4; HL-60 PAD; Peptidylarginine Deiminase IV; Protein-arginine Deiminase type IV; PADI4; PADI5; PDI5
UNIProt ID: Q9UM07
Research Areas: Signal Transduction; epigenetics and nuclear signal; metabolism;
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-6His
Accession: Q9UM07
Background: Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.
Sequence: Met 1-Pro663
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris, 500mM NaCl, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 76.2 kDa
Observed MW: 78 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only